Closing Summation, RECOVER III, and Intro to RECOVER IV

Presented by William O'Neill, MD

William O’Neill, MD, reviews RECOVER III data showing improved outcomes associated with best practices, notably, improved survival in patients with AMI cardiogenic shock associated with adoption of best practice protocols in post-PMA vs pre-PMA cohorts:

  • Earlier shock recognition and initiation of Impella support
  • Less use of inotropes and vasopressors
  • More Impella pre-PCI and complete revascularization
  • More use of right heart catheterization (RHC) to optimize therapy

These led to a lower incidence of adverse events:

  • Less acute renal failure
  • Less bleeding requiring transfusion
  • Fewer vascular complications requiring surgery

Dr. O’Neill also introduces RECOVER IV, a randomized controlled trial in which patients with AMI cardiogenic shock will be randomized to the active treatment group using the NCSI protocol or the control group, in which the patient will be treated with other treatment approaches, including any kind of circulatory support other than Impella®.

Dr. O’Neill is the medical director of the Center for Structural Heart Disease, Henry Ford System, Detroit, Michigan.

This video is part of a series: Achieving >70% AMI-CS Survival: Best Practices From Around the World

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To learn more about the Impella® platform of heart pumps, including important risk and safety information associated with the use of the devices, please visit: abiomed.com/important-safety-information

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