Contemporary Practices of HR-PCI With Percutaneous MCS: Results From PROTECT III, the Largest Prospective Multi-Center Single-Arm Study

Presented by Jeffrey Moses, MD

Jeffrey W. Moses, MD, presents results from the PROTECT III trial which included 1,143 patients undergoing elective non-emergent PCI with Impella® from 45 sites. PROTECT III represents the largest prospective study of the use of Impella mechanical circulatory support for high-risk PCI in the real world with contemporary best practices. From this data, Dr. Moses highlights the following:

  • PROTECT III patients were older with more comorbidities and more complex lesions, and underwent more extensive revascularization than PROTECT II patients
  • PROTECT III 90-day MACCE rates were improved compared to PROTECT II in both unmatched and propensity matched cohorts
  • PROTECT III procedural outcomes show improved in-hospital safety with significantly fewer vascular and bleeding complications compared to PROTECT II

Dr. Moses is the John and Myrna Daniels Professor of Cardiology and director of interventional cardiac therapeutics at Columbia University Medical center as well as the director of complex coronary interventions at St. Francis Hospital in Roslyn, NY.

This video is part of a series: Protected PCI in COVID-19 Era: The Rise in Importance of Complete Revascularization

View our full TCT Connect coverage on ProtectedPCI.com.

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To learn more about the Impella® platform of heart pumps, including important risk and safety information associated with the use of the devices, please visit: abiomed.com/important-safety-information

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