Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance

The Importance of Hemodynamic Monitoring

Dr. Elazer Edelman is a senior attending physician in the intensive care unit at Brigham and Women's Hospital, a professor at Harvard Medical School, and a professor and director of the Institute for Medical Engineering and Science at MIT. His publication "Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance" was featured in the Biomedical Engineering Society Journal in April, and he recently joined a conversation with Dr. Seth Bilazarian to discuss how achieving optimal therapeutic benefit requires metrics of state to guide titration and weaning of support. According to Dr. Edleman's research, using the transvalvular positioning of a percutaneous ventricular assist device (pVAD), heart interactions are leveraged to determine cardiac output (CO) and systemic vascular resistance (SVR) near-continuously without disrupting therapeutic function.

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