Clinical Research

PROTECT IV Randomized Controlled Trial RECOVER IV Randomized Controlled T...

Mechanical Circulatory Support in Refractory Cardiogenic Shock

Extrapolations for COVID-19 from Influenza Virus-Related Myocarditis Professor Dr. Andreas Schäfer an...

Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance

The Importance of Hemodynamic Monitoring Dr. Elazer Edelman is a senior attending physician in the intensive care unit...

SmartAssist FAQs

Answering Questions About LV Metrics Jo Kajewski, an Abiomed advanced Impella® trainer, answers some...

Impella Designed for Blood Compatibility

Troubleshooting Suspected Hemolysis In this educational video, Jessica Page, an advanced Impella trai...

LVEDP and Impella SmartAssist Technology

How is the LV waveform derived and LVEDP measured? Jo Kajewski, an Abiomed advanced Impella trainer,...

Weaning with the SmartAssist Platform

How to Use the SmartAssist Trend Screen This video explains how to use the SmartAssist® trend...

When the Doctor is the Patient

A Patient’s EF Improves from 5% to 55% with Biventricular Impella Support Babu Eladasari, MD, BS, FACP, MBBS presents...

Impella RP® as Therapy for COVID-19 Patients with Right Heart Failure

Dr. Amir Kaki, an interventional cardiologist and director of mechanical circulatory support at Ascension St....

Outcomes of Impella-Supported Nonemergent High-Risk PCI

No Increase in Mortality with Impella To address questions regarding whether there is a difference in mortalit...

COVID-19-Related Respiratory and Cardiac Failure

Roles for Advanced Therapy Keshava Rajagopal, MD, PhD discusses the use of conventional management st...

Impella RP® Treatment for a COVID-19 Patient in Cardiogenic Shock

Improving Hemodynamics and the Total Metabolic Milieu Dr. Dimitri Karmpaliotis discusses the challeng...

Activating Cath Labs for Elective Procedures Amid COVID-19

Ramping Up Procedures and Selecting Patients Two cardiologists share best practices for rebooting cath labs for...

Activating Cath Labs for Emergent Procedures Amid COVID-19

Best Practices for STEMI and RV Dysfunction As cath labs reopen to handle emergent procedures...

Impella Support for COVID-19 Myocarditis

Dr. Amit Pawale presents the case of a 56-year-old male with COVID-19 myocarditis. Dr. Pawale...

Volume Management in Cardiogenic Shock Patients

MCS and Volume Considerations in the ICU How do you assess and manage volume in...

Treatment of a COVID-19 Patient Using Impella 5.5 with SmartAssist

David D’Alessandro, MD presents the case of a 44-year-old woman presenting to the ER 8 days after the onset of...

Management of Patients During COVID-19 Crisis: Focus on Cardiovascular Complications

During this call on April 10, 2020 with Global Medical Directors, Dr. Seth Bilazarian focuses on management of...

COVID-19 Cardiovascular Manifestations Panel

COVID-19 Cardiovascular Manifestations: Considerations for MCS Several physicians discuss the cardiovascular m...

Protected PCI from the Patient’s Perspective

Mary Finally Regains QOL after Complete Revascularization Mary Hanel had her first heart attack in her forties and dou...

Increasing Survival in Cardiogenic Shock through Escalation

Escalation Strategies that Increase Unloading Mark Anderson, MD, discusses how cardiac surger...

Clinical Data Insights

Factors Involved in Real World Data Comparisons The clinical community is eager to have more information about clinica...

Minimizing Hemolysis

Impella Position is Key Marvin Slepian, MD, who specializes in blood rheology, discusses the nature a...

Information for Physicians: Medical Office Review of Dhruva et al.

On February 10, the Dhruva et al. paper analyzing CATH PCI and Chest Pain registry data published in JAMA. This paper has simil...

Managing Impella® Position

Using Imaging and the AIC for Positioning Jo Kajewski, an Advanced Impella Trainer, uses the Abiomed...

Bleeding and Vascular Complications

A Look at Impella® Data Over Time Daniel Raess, MD, presents clinical data on Impe...

Nursing Video: Calculating Total Heparin Rate

How to Account for Impella Delivered Heparin When supporting a patient with Impella, it is important to account for th...

Multivessel Versus Culprit Vessel PCI

Is Multivessel PCI with Impella Support Safe in Cardiogenic Shock? Alejandro Lemor, MD, MS, discusses...

Impella® Patient Management

Questions to Ask When Caring for an Impella® Patient Jason Richard, an advanced Impella® trainer at Abiomed, reviews q...

PROTECT Series of Clinical Studies Provides Mounting Evidence for Impella Support in High-risk PCI

Looking at the data from the PROTECT Series—PROTECT I1, PROTECT II RCT2, and PROTECT III—William O’Neill,...

National Cardiogenic Shock Initiative Update

Dr. Bill O’Neill Discusses Ongoing Progress in NCSI Bill O’Neill, MD presents some of the overall out...

Publication Review: Amin Analysis on Impella and IABP

Review of Trends, Variation and Outcomes in Impella® Use Dr. Seth Bilazarian, Abiomed’s Chief Medical Officer...

Cost-effectiveness and Impella

Dr. George Vetrovec Discusses Impella Cost Effectiveness Dr. George Vetrovec, professor of medicine, emeritus, at Virg...

Techniques to Reduce Bleeding with Large Bore Access Devices

Dr. Amir Kaki Discusses Techniques to Reduce Bleeding Dr. Amir Kaki outlines the factors that have led to reductions i...

Contemporary Landscape of PCI and RESTORE EF

TCT 2019 Presentation from SCAI President Dr. Ehtisham Mahmud At TCT 2019, Dr. Ehtisham Mahmud gave a...

NCSI Findings Regarding Right Ventricular Dysfunction

About 40% of AMICS Patients Develop Right Ventricular Dysfunction Dr. Babar Basir, an interventionalist at Henry Ford...

Does Impella Affect Predicted AKI Risk?

Study Shows a 78% Risk Decrease in Overall Incidence of Post-procedural AKI Dr. Michael Flaherty pres...

Impella Connect® and SmartAssist®

Facilitating Impella® Support in a Cardiogenic Shock Case...

Impella Support and Acute Kidney Injury During High-Risk PCI

Results from the cVAD Study™ on Renal Protection Dr. Michael Flaherty presents data on...

PROTECT III

PROTECT III Data Continues to Demonstrate Reduced MACCE with Impella® Dr. Jeffrey Popma examines the curren...

Case Video: Impella Connect® Was Key to Troubleshooting

Remote Support in a Snowstorm As an early user of...

Right Heart Hemodynamics

Visualizing Hemodynamics During Biventricular Support Dr. Daniel Burkhoff presents a graphic represen...

Demonstrating Right Heart Hemodynamics

Key to Recognizing Need for Biventricular Support Dr. Daniel Burkhoff walks through a HARVI...

Echocardiography for the Impella Heart Pump

Assessing Impella Position with Echo Michael Galvin RDCS, a cardiac sonographer and Abiomed Clinical Support Center Sp...

Summary of AKI Data with Impella Unloading

Study shows lower than predicted incidence of post-procedural AKI in Protected PCI patients Dr. Seth Bilazarian, chief...

Roma Verona Impella ProPCI Study Summary with Dr. Burzotta and Dr. Trani

Complete Revascularization Associated with Significant Improvement in LVEF and Long-term Survival In this video, Dr. A...

Quick Tips: Impella CP with SmartAssist®

Impella CP with SmartAssist® Experience Inder Singh, MD, MS, interventional cardiologist a...

New Clinical Publication: Long-Term Outcomes of Complex, High-Risk PCI Patients

Dr. Shon Chakrabarti shares information on a recent publication from the Journal of Interventional Cardiology by Dr. Francesco...

New Data from NCSI Demonstrates 72% Survival with 98% Native Heart Recovery

New data from the National Cardiogenic Shock Initiative Study (NCSI) on 171 consecutive AMI cardiogenic shock (AMICS) patients...

Dr. Seth Bilazarian on the recent Circulation paper by Dr. Schrage/Dr. Ibrahim

Dr. Seth Bilazarian discusses a recent paper published in Circulation by Drs. Benedikt Schrage, Karim Ibrahim, et. al....

Analysis of Outcomes for 15,259 U.S. Patients with AMICS Supported with the Impella Device

Dr. William O’Neill outlines his recent publication of 15,529 AMI cardiogenic shock patients from the Impella Quality (IQ) data...

Use of Impella® Device to Assess Left Ventricular Function: A Proof-of-Concept Study

Left ventricular end-diastolic pressure (LVEDP) refers to the pressure in the LV at the end of diastolic filling and immediatel...

Hemodynamic Benefits of Impella RP® Heart Pump for Right Heart Failure

Dr. William O’Neill and Dr. Mark Anderson, co-principle investigators of the RECOVER-RIGHT clinical trial, and Dr. Seth Bilazar...

Dr. Tim Larkin Discusses Timing of Impella RP® Placement

Dr. Tim Larkin of Edward Hospital explains his timing protocol for Impella RP® placement in this physician Q&A s...

Dr. Bill O’Neill Discusses Recovery Time from RV and LV Shock with Impella RP® Support

In this physician Q&A session, Dr. Bill O’Neill discusses recovery considerations as well as time to recovery following Imp...

Impella RP® Weaning Recommendations from Dr. Tim Larkin

Dr. Tim Larkin of Edward Hospital describes his weaning protocol for the Impella RP® during this physician Q&A session. In...

Dr. Thorsten Siess, Abiomed’s CTO and Inventor of Impella® Shares his Insights on the Impella® Platform of Devices

Dr. Thorsten Siess, Abiomed’s Chief Technology Officer and inventor of Impella® discusses how the world's smallest heart pump t...

How Impella 2.5® Provides Hemodynamic Support During Protected PCI

Watch this brief anatomical video to learn how Impella 2.5 provides hemodynamic support during Protected PCI....

Roundtable Discusses Protected PCI for High-Risk Patients

In the video below, Dr. John Lasala from Washington University, St. Louis, Missouri, hosts a roundtable discussion on Protected...

About This Site

Welcome to the Protected PCI community, the largest source of education and reference materials on pVADs and the Impella® platf...

About Impella

Provides direct left ventricular unloading by pulling blood from the left ventricle and expelling it into the aorta, incr...

Editorial Board

Editorial Board Members  ...